Wednesday, 23 April 2014

cochlear implant capable of regrowing auditory nerves




Cochlear implants facilitate the deaf to hear by artificial means, but a brand new way to use the prevailing technology could show promise for sooner or later restoring patients' natural hearing. By applying electrical impulses from a tube-shaped structure implant to administer gene therapy, a team of researchers at the University of New South Wales, led by PhD student Jeremy pinyon and supervised by prof Housley, has regrown broken auditory nerves in adult guinea pigs, an animal that has a similar sensory system to humans.

The team changed an existing tube-shaped structure implant to administer a kind of therapy referred to as close-field electroporation (CFE) gene therapy. Electroporation involves administering electrical pulses to a cell membrane to extend its permeability. this enables new factor constructs to be delivered to the membrane, which inspires growth.

When it involves the tube, a family of proteins referred to as neurotrophins will regenerate auditory nerve endings, however administering treatment — either by drug or viral-based gene therapy — isn't safe. However, using the tube implant has allowed professor Housley's team to administer the treatment in an exceedingly safe, localized fashion.

"People with tube implants act with understanding speech, however their perception of pitch is poor, in order that they typically miss out on the enjoyment of music.

We hope this research brigs lot of positive outcome for those who had to depend on exter d
evises to Hear sound or to listen to music

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