Sunday, 30 March 2014

Lab-made mini human to screen medicine, toxins





Work begins on Athena, a $19 million project that seeks to make artificial organs that work jointly within a human-like check dummy that might cut back reliance on animal testing.

Something known as the Advanced Tissue-engineered Human Ectypal Network instrument project would possibly sound sort of a secret weapon being developed by S.H.I.E.L.D. In fact, it is a project being developed here within the real would that might amendment the method new medication and virulent agents are screened.

Led by researchers at the Los Alamos National Laboratory, the Athena project aims to make mini versions of 4 artificial organs -- liver, lung, heart, and urinary organ -- which will be connected within a synthetic trunk. every organ will be about the scale of a smartphone screen, in step with LANL, and be connected by tube crammed with liquid. all at once, the Athena "body" ought to be sufficiently little to sit down on a table.

"By developing this 'homo minutus,' we are stepping on the far side the requirement for animal or Petri dish testing: There are large edges in developing drug and toxicity analysis systems which will mimic the response of actual human organs," Rashi Iyer, a senior scientist at LANL leading the Athena organ project, aforementioned in an exceedingly statement.

The artificial mini human will be engineered over the five-year course of the project, that features a budget of $19 million and is supported by the Defense Threat Reduction Agency, a subdivision of the Department of Defense (not quite S.H.I.E.L.D., however it is the best we got).

"The final goal is to make a respiratory organ that breathes, a heart that pumps, a liver that metabolizes, and a urinary organ that excretes -- all connected by a tube infrastructure a lot of adore the method blood vessels connect our organs," Iyer side. "While some skeptics would possibly believe that this can be a utopian dream... the team is assured that this can be so realizable."

vitro model that enables us to live human liver responses to medication and toxins that can't be replicated by a layer of cells growing on plastic."

Vanderbilt is additionally collaborating with the LANL to make a synthetic blood which will flow through the four mechanical organs.

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